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S. Korean, Israeli Scientists Find New Mechanism to Suppress Tumor Growth

Written: 2015-04-19 13:14:19Updated: 2015-04-19 14:51:42

S. Korean, Israeli Scientists Find New Mechanism to Suppress Tumor Growth

South Korean and Israeli scientists jointly uncovered a new mechanism that suppresses growth of cancer cells.

Seoul National University (SNU) said on Sunday that a team led by Aaron Ciechanover, an Israeli biochemist and winner of the 2004 Nobel Prize in Chemistry, and Professor Kwon Yong-tae found the mechanism.

The scientists said that NF-κB is a key transcriptional regulator involved in inflammation and cell proliferation, survival, and transformation, and overexpression of KPC1, an enzyme involved in processing NF-κB, appears to suppress growth of tumor cells.

The findings of a joint research by SNU and Technion (Israel Institute of Technology) appeared on the April 10 edition of Cell.
 
 

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